Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK3 | P27361 | 19/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | ULK1 | O75385 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18256256 | 0.87 | MAPK3 (0.70) | MAPK3MAPK1ULK1 | |
| SCHEMBL15948438 | 0.85 | MAPK3 (0.69) | MAPK3MAPK1ULK1 | |
| SCHEMBL18256234 | 0.84 | MAPK3 (0.72) | MAPK3MAPK1ULK1 | |
| SCHEMBL17533900 | 0.83 | MAPK3 (0.85) | MAPK3MAPK1 | |
| SCHEMBL17533879 | 0.81 | MAPK3 (0.62) | MAPK3MAPK1 | |
| SCHEMBL19217383 | 0.80 | MAPK3 (0.82) | MAPK3MAPK1 | |
| SCHEMBL18256214 | 0.79 | MAPK3 (0.58) | MAPK3MAPK1ULK1 | |
| SCHEMBL21009863 | 0.79 | MAPK3 (0.75) | MAPK3MAPK1 | |
| SCHEMBL19176665 | 0.78 | MAPK3 (0.72) | MAPK3MAPK1 | |
| SCHEMBL19176653 | 0.78 | MAPK3 (0.82) | MAPK3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016025640-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | CELGENE AVILOMICS RESEARCH, INC. (US) | 2016-02-18 | — | — | WO | disclosed |