Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 20/20 | 0.74 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17536563 | 1.00 | AR (0.74) | ARCRBN | |
| SCHEMBL24266797 | 1.00 | AR (0.74) | ARCRBN | |
| SCHEMBL31061198 | 0.93 | AR (0.73) | ARCRBN | |
| SCHEMBL22197929 | 0.93 | AR (0.73) | ARCRBN | |
| SCHEMBL17519965 | 0.90 | AR (0.73) | ARCRBN | |
| SCHEMBL18473049 | 0.90 | AR (0.73) | ARCRBN | |
| SCHEMBL17941080 | 0.90 | AR (0.73) | ARCRBN | |
| SCHEMBL17523083 | 0.90 | AR (0.73) | ARCRBN | |
| SCHEMBL17519966 | 0.90 | AR (0.73) | ARCRBN | |
| SCHEMBL25315777 | 0.89 | AR (0.72) | ARCRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160058872-A1 | IMIDE-BASED MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. | 2016-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160058872-A1 | IMIDE-BASED MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE | CRBN, MDM2, UBE2N | AR 3905/4885CRBN 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.