SCHEMBL17537270

SCHEMBL17537270

Cc1ccc(S(=O)(=O)N[C@@H](CC(=O)O)CC(=O)NC(C)(C)C)cc1

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PSMB8 P28062 18/20 0.57
PSMB5 P28074 15/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18759316 0.83 PSMB8 (0.67) PSMB8PSMB5
SCHEMBL17537269 0.81 PSMB8 (0.49) PSMB8PSMB5
SCHEMBL4343926 0.80 CA9 (0.51)
SCHEMBL4343932 0.80 CA9 (0.51)
Hydrochloric Acid SCHEMBL6422714 0.79 SLC1A3 (0.52)
Hydrochloric Acid SCHEMBL6422709 0.79 SLC1A3 (0.52)
SCHEMBL4869315 0.77 SLC1A3 (0.48)
Iodide SCHEMBL6421257 0.77 SLC1A3 (0.48)
SCHEMBL4869319 0.77 SLC1A3 (0.48)
SCHEMBL18759268 0.75 PSMB8 (0.64) PSMB8PSMB5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016028571-A2 DIPEPTIDOMIMETICS AS INHIBITORS OF HUMAN IMMUNOPROTEASOMES CORNELL UNIVERSITY (US) 2016-02-25 WO disclosed