Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 20/20 | 0.62 |
| ▸ | FGF2 | P09038 | 2/20 | 0.62 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.62 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17539414 | 0.94 | FGFR1 (0.60) | FGFR1FGF2FGFR4FGFR3 | |
| SCHEMBL17539403 | 0.93 | FGFR1 (0.63) | FGFR1FGF2FGFR4FGFR3 | |
| SCHEMBL17539359 | 0.92 | FGFR1 (0.61) | FGFR1FGF2FGFR4FGFR3 | |
| SCHEMBL17539440 | 0.91 | FGFR1 (0.60) | FGFR1FGF2FGFR4FGFR3 | |
| SCHEMBL17539563 | 0.90 | FGFR1 (0.66) | FGFR1FGF2FGFR4FGFR3 | |
| SCHEMBL17539453 | 0.88 | FGFR1 (0.60) | FGFR1FGF2FGFR4FGFR3 | |
| SCHEMBL17539547 | 0.88 | FGFR1 (0.68) | FGFR1FGF2FGFR4FGFR3 | |
| SCHEMBL17539471 | 0.88 | FGFR1 (0.65) | FGFR1FGF2FGFR4FGFR3 | |
| SCHEMBL17539552 | 0.88 | FGFR1 (0.59) | FGFR1FGF2FGFR4FGFR3 | |
| SCHEMBL17539429 | 0.87 | FGFR1 (0.62) | FGFR1FGF2FGFR4FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016027780-A1 | 4-AMINOPYRIDINE DERIVATIVE | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 2016-02-25 | — | — | WO | disclosed |