Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 20/20 | 0.67 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.62 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.62 |
| ▸ | KDR | P35968 | 1/20 | 0.62 |
| ▸ | FGF2 | P09038 | 1/20 | 0.61 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17539349 | 0.97 | FGFR1 (0.68) | FGFR1FGFR2FGFR3KDRFGF2 | |
| SCHEMBL17539622 | 0.95 | FGFR1 (0.69) | FGFR1FGFR2FGFR3KDRFGF2 | |
| SCHEMBL17539500 | 0.95 | FGFR1 (0.66) | FGFR1FGFR3FGF2FGFR4 | |
| SCHEMBL17539431 | 0.94 | FGFR1 (0.66) | FGFR1FGFR3FGF2FGFR4 | |
| SCHEMBL17539646 | 0.92 | FGFR1 (0.67) | FGFR1FGFR2FGFR3KDRFGF2 | |
| SCHEMBL17539367 | 0.91 | FGFR1 (0.67) | FGFR1FGFR2FGFR3KDRFGF2 | |
| SCHEMBL17539494 | 0.91 | FGFR1 (0.68) | FGFR1FGFR3FGF2FGFR4 | |
| SCHEMBL17539443 | 0.91 | FGFR1 (0.68) | FGFR1 | |
| SCHEMBL17539354 | 0.91 | FGFR1 (0.67) | FGFR1 | |
| SCHEMBL17539357 | 0.91 | FGFR1 (0.67) | FGFR1FGFR3FGF2FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016027780-A1 | 4-AMINOPYRIDINE DERIVATIVE | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 2016-02-25 | — | — | WO | disclosed |