Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 20/20 | 0.51 |
| ▸ | FGF2 | P09038 | 1/20 | 0.46 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.46 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17539373 | 0.91 | FGFR1 (0.46) | FGFR1FGF2FGFR4FGFR3 | |
| SCHEMBL17539536 | 0.86 | FGFR1 (0.40) | FGFR1FGF2FGFR4FGFR3 | |
| SCHEMBL17539501 | 0.86 | FGFR1 (0.51) | FGFR1FGF2FGFR4FGFR3 | |
| SCHEMBL17539553 | 0.86 | FGFR1 (0.46) | FGFR1FGF2FGFR4FGFR3 | |
| SCHEMBL17539542 | 0.85 | FGFR1 (0.43) | FGFR1FGF2FGFR4FGFR3 | |
| SCHEMBL17539426 | 0.85 | FGFR1 (0.58) | FGFR1FGF2FGFR4FGFR3 | |
| SCHEMBL17539535 | 0.85 | FGFR1 (0.47) | FGFR1 | |
| SCHEMBL17539424 | 0.85 | FGFR1 (0.54) | FGFR1 | |
| SCHEMBL17539556 | 0.85 | FGFR1 (0.50) | FGFR1 | |
| SCHEMBL17539453 | 0.84 | FGFR1 (0.60) | FGFR1FGF2FGFR4FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016027780-A1 | 4-AMINOPYRIDINE DERIVATIVE | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 2016-02-25 | — | — | WO | disclosed |