Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 20/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17539631 | 0.88 | FGFR1 (0.44) | FGFR1 | |
| SCHEMBL17539653 | 0.85 | FGFR1 (0.46) | FGFR1 | |
| SCHEMBL17539621 | 0.84 | FGFR1 (0.53) | FGFR1 | |
| SCHEMBL17539581 | 0.82 | FGFR1 (0.60) | FGFR1 | |
| SCHEMBL17539668 | 0.82 | FGFR1 (0.46) | FGFR1 | |
| SCHEMBL17539665 | 0.82 | FGFR1 (0.55) | FGFR1 | |
| SCHEMBL17539584 | 0.82 | FGFR1 (0.65) | FGFR1 | |
| SCHEMBL17539637 | 0.82 | FGFR1 (0.57) | FGFR1 | |
| SCHEMBL17539669 | 0.81 | FGFR1 (0.65) | FGFR1 | |
| SCHEMBL17539604 | 0.81 | FGFR1 (0.64) | FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016027780-A1 | 4-AMINOPYRIDINE DERIVATIVE | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 2016-02-25 | — | — | WO | disclosed |