SCHEMBL17539737

SCHEMBL17539737

c1ccc(-c2ccc(-c3nc(-c4cccc(-c5cccc(-n6c7ccccc7c7ccccc76)c5)c4)cc(-c4cccc(-n5c6ccccc6c6ccccc65)c4)n3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
MEN1 O00255 6/20 0.44
KMT2A Q03164 6/20 0.44
ALDH1A1 P00352 5/20 0.44
MAPT P10636 5/20 0.44
HPGD P15428 5/20 0.44
LMNA P02545 2/20 0.44
GLA P06280 1/20 0.44
NTSR1 P30989 1/20 0.43
MAOB P27338 2/20 0.37
PDE10A Q9Y233 1/20 0.37
ADORA2A P29274 1/20 0.37
ADORA1 P30542 1/20 0.37
MAOA P21397 1/20 0.37
NPSR1 Q6W5P4 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
CYP2C19 P33261 1/20 0.36
ABCG2 Q9UNQ0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15458707 1.00 KDM4E (0.46) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL15458428 1.00 KDM4E (0.46) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL15458566 1.00 KDM4E (0.46) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL17539728 1.00 KDM4E (0.46) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL15458420 1.00 KDM4E (0.46) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL23759842 0.99 MEN1 (0.47) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL17539778 0.99 MEN1 (0.47) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL15458570 0.99 MEN1 (0.47) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL17539760 0.99 MEN1 (0.47) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL17539780 0.99 MEN1 (0.47) KDM4EATML3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180123054-A1 COMPOSITION FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY AND LIGHTING MITSUBISHI CHEMICAL CORPORATION (JP) 2018-05-03 US disclosed
US-20180123054-A1 COMPOSITION FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY AND LIGHTING MITSUBISHI CHEMICAL CORPORATION (JP) 2018-05-03 US disclosed
US-9899606-B2 Composition for organic electroluminescent element, organic electroluminescent element, display and lighting MITSUBISHI CHEMICAL CORPORATION (JP) 2018-02-20 US disclosed
US-9899606-B2 Composition for organic electroluminescent element, organic electroluminescent element, display and lighting MITSUBISHI CHEMICAL CORPORATION (JP) 2018-02-20 US disclosed
US-20160043325-A1 COMPOSITION FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY AND LIGHTING MITSUBISHI CHEMICAL CORPORATION (JP) 2016-02-11 US disclosed
US-20160043325-A1 COMPOSITION FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY AND LIGHTING MITSUBISHI CHEMICAL CORPORATION (JP) 2016-02-11 US disclosed