Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 18/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.49 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21350635 | 0.85 | SLC22A12 (0.54) | SLC22A12SLC22A6SLC22A11ABCG2CYP4F2 | |
| SCHEMBL17540560 | 0.85 | SLC22A12 (0.69) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL19240219 | 0.81 | SLC22A12 (0.58) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL17545598 | 0.80 | SLC22A12 (0.74) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL18105453 | 0.77 | SLC22A12 (0.77) | SLC22A12 | |
| SCHEMBL28238871 | 0.77 | CCNC (0.59) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL17540598 | 0.75 | SLC22A12 (0.61) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL14919143 | 0.74 | SLC22A12 (0.74) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL26661046 | 0.74 | CYP4F2 (0.63) | CYP4F2CYP4A11 | |
| SCHEMBL28642447 | 0.73 | CCNC (0.79) | SLC22A12CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106573908-B | Carboxylic acid compound, and preparation method and use thereof | 益方生物科技(上海)股份有限公司 | 2021-02-05 | — | — | CN | disclosed |
| US-20180022736-A1 | CARBOXYLIC ACID COMPOUND, METHOD FOR PREPARATION THEREOF, AND USE THEREOF | InventisBio Co., Ltd. (CN) | 2018-01-25 | — | — | US | disclosed |
| US-20180022736-A1 | CARBOXYLIC ACID COMPOUND, METHOD FOR PREPARATION THEREOF, AND USE THEREOF | InventisBio Co., Ltd. (CN) | 2018-01-25 | — | — | US | disclosed |
| US-20180022736-A1 | CARBOXYLIC ACID COMPOUND, METHOD FOR PREPARATION THEREOF, AND USE THEREOF | InventisBio Co., Ltd. (CN) | 2018-01-25 | — | — | US | disclosed |
| US-9856239-B1 | Carboxylic acid compound, method for preparation thereof, and use thereof | INVENTISBIO SHANGHAI LTD. (CN) | 2018-01-02 | — | — | US | disclosed |
| US-9856239-B1 | Carboxylic acid compound, method for preparation thereof, and use thereof | INVENTISBIO SHANGHAI LTD. (CN) | 2018-01-02 | — | — | US | disclosed |
| US-9809580-B2 | Carboxylic acid compound, method for preparation thereof, and use thereof | INVENTISBIO SHANGHAI LTD. (CN) | 2017-11-07 | — | — | US | disclosed |
| US-9809580-B2 | Carboxylic acid compound, method for preparation thereof, and use thereof | INVENTISBIO SHANGHAI LTD. (CN) | 2017-11-07 | — | — | US | disclosed |
| US-9809580-B2 | Carboxylic acid compound, method for preparation thereof, and use thereof | INVENTISBIO SHANGHAI LTD. (CN) | 2017-11-07 | — | — | US | disclosed |
| US-20170233376-A1 | CARBOXYLIC ACID COMPOUND, METHOD FOR PREPARATION THEREOF, AND USE THEREOF | InventisBio Co., Ltd. (CN) | 2017-08-17 | — | — | US | disclosed |
| US-20170233376-A1 | CARBOXYLIC ACID COMPOUND, METHOD FOR PREPARATION THEREOF, AND USE THEREOF | InventisBio Co., Ltd. (CN) | 2017-08-17 | — | — | US | disclosed |
| US-20170233376-A1 | CARBOXYLIC ACID COMPOUND, METHOD FOR PREPARATION THEREOF, AND USE THEREOF | InventisBio Co., Ltd. (CN) | 2017-08-17 | — | — | US | disclosed |
| EP-3181557-A1 | CARBOXYLIC ACID COMPOUND, METHOD FOR PREPARATION THEREOF, AND USE THEREOF | Shanghai Shaletech Technology Co., Ltd. (CN) | 2017-06-21 | — | — | EP | disclosed |
| EP-3181557-A1 | CARBOXYLIC ACID COMPOUND, METHOD FOR PREPARATION THEREOF, AND USE THEREOF | Shanghai Shaletech Technology Co., Ltd. (CN) | 2017-06-21 | — | — | EP | disclosed |
| WO-2016023460-A1 | CARBOXYLIC ACID COMPOUND, METHOD FOR PREPARATION THEREOF, AND USE THEREOF | 上海页岩科技有限公司 | 2016-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233376-A1 | CARBOXYLIC ACID COMPOUND, METHOD FOR PREPARATION THEREOF, AND USE THEREOF | CA7, CYP2C9, CA9 | SLC22A12 251/4885SLC22A6 205/4885SLC22A11 178/4885 |
| US-20180022736-A1 | CARBOXYLIC ACID COMPOUND, METHOD FOR PREPARATION THEREOF, AND USE THEREOF | CA7, CYP2C9, CA9 | SLC22A12 251/4885SLC22A6 205/4885SLC22A11 178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.