Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 20/20 | 0.59 |
| ▸ | PPARG | P37231 | 16/20 | 0.58 |
| ▸ | PPARD | Q03181 | 14/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17540655 | 1.00 | PPARA (0.59) | PPARAPPARGPPARD | |
| SCHEMBL17540650 | 1.00 | PPARA (0.59) | PPARAPPARGPPARD | |
| SCHEMBL17540676 | 1.00 | PPARA (0.59) | PPARAPPARGPPARD | |
| SCHEMBL17540651 | 0.91 | PPARA (0.47) | PPARAPPARGPPARD | |
| SCHEMBL17540656 | 0.91 | PPARA (0.47) | PPARAPPARGPPARD | |
| SCHEMBL17540666 | 0.91 | PPARA (0.47) | PPARAPPARGPPARD | |
| SCHEMBL17792288 | 0.90 | PPARA (0.58) | PPARAPPARGPPARD | |
| SCHEMBL17540631 | 0.90 | PPARA (0.58) | PPARAPPARGPPARD | |
| SCHEMBL17792275 | 0.90 | PPARA (0.58) | PPARAPPARGPPARD | |
| SCHEMBL14332309 | 0.88 | PPARA (0.58) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160051529-A1 | PPAR-SPARING THIAZOLIDINEDIONES AND COMBINATIONS FOR THE TREATMENT OF NEURODEGENERATIVE AND OTHER METABOLIC DISEASES | CIRIUS THERAPEUTICS, INC. | 2016-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160051529-A1 | PPAR-SPARING THIAZOLIDINEDIONES AND COMBINATIONS FOR THE TREATMENT OF NEURODEGENERATIVE AND OTHER METABOLIC DISEASES | PPARD, PPARG, PPARA | PPARA 3/4885PPARG 2/4885PPARD 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.