Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.59 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.59 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8178988 | 0.89 | PDE4A (0.71) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL15969626 | 0.84 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL11755700 | 0.84 | POLB (0.68) | KMT2AMEN1POLBTP53NPC1 | |
| SCHEMBL15572275 | 0.82 | TSHR (0.67) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL15595867 | 0.82 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL14248660 | 0.81 | CA12 (0.71) | ALDH1A1NR1H4RAB9AGAAHTT | |
| SCHEMBL30708091 | 0.81 | CA12 (0.71) | ALDH1A1NR1H4RAB9AGAAHTT | |
| SCHEMBL31465194 | 0.80 | HTT (0.61) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL6138174 | 0.80 | HTT (0.61) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL15573893 | 0.80 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4DKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016033190-A1 | RADIOTRACER COMPOUNDS | EISAI, INC. (JP) | 2016-03-03 | — | — | WO | disclosed |
| WO-2016033190-A1 | RADIOTRACER COMPOUNDS | EISAI, INC. (JP) | 2016-03-03 | — | — | WO | disclosed |