SCHEMBL17547679

SCHEMBL17547679

Cc1ccc2c(c1)CN(S(=O)(=O)c1cccs1)C(Cc1ccccc1)CN2Cc1cnc[nH]1

nearest known ligand 0.80

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FNTA P49354 20/20 0.80
FNTB P49356 20/20 0.80
HRAS P01112 1/20 0.80
KRAS P01116 1/20 0.80
PGGT1B P53609 1/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10039032 0.91 FNTA (0.80) FNTAFNTBHRASKRASPGGT1B
SCHEMBL29171478 0.90 FNTA (0.79) FNTAFNTBHRASKRASPGGT1B
Bms-214662 SCHEMBL16499911 0.89 FNTA (1.00) FNTAFNTBHRASKRASPGGT1B
Bms-214662 SCHEMBL94663 0.89 FNTA (1.00) FNTAFNTBHRASKRASPGGT1B
Bms-214662 SCHEMBL30498791 0.88 FNTA (0.99) FNTAFNTBHRASKRASPGGT1B
SCHEMBL22050803 0.81 FNTA (0.86) FNTAFNTBHRASKRASPGGT1B
SCHEMBL12193488 0.78 FNTA (0.65) FNTAFNTBHRASKRASPGGT1B
SCHEMBL13300962 0.77 FNTA (0.80) FNTAFNTBHRASKRASPGGT1B
SCHEMBL15977117 0.77 FNTA (0.77) FNTAFNTBHRASKRASPGGT1B
SCHEMBL13186538 0.75 FNTA (0.58) FNTAFNTBHRASKRASPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160058751-A1 COMPOSITION AND METHOD FOR TREATING CANCER CELLWORKS GROUP, INC. (US) 2016-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160058751-A1 COMPOSITION AND METHOD FOR TREATING CANCER KRAS, NRAS, TP53 FNTA 1114/4885FNTB 1259/4885HRAS 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.