Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL685093 | 0.84 | TSHR (0.55) | TSHRALDH1A1THRBADRB2ADRB1 | |
| SCHEMBL28614099 | 0.83 | TSHR (0.47) | TSHRALDH1A1THRBADRB2ADRB1 | |
| SCHEMBL94906 | 0.82 | TSHR (0.68) | TSHRALDH1A1THRBUSP2CYP3A4 | |
| SCHEMBL24754925 | 0.82 | TSHR (0.53) | TSHRALDH1A1THRBADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL1345735 | 0.82 | TSHR (0.53) | TSHRALDH1A1THRBADRB2ADRB1 | |
| SCHEMBL11386675 | 0.81 | TSHR (0.45) | TSHRALDH1A1THRBADRB2ADRB1 | |
| SCHEMBL11386676 | 0.81 | TSHR (0.45) | TSHRALDH1A1THRBADRB2ADRB1 | |
| SCHEMBL11308312 | 0.81 | TSHR (0.49) | TSHRALDH1A1THRBADRB2ADRB1 | |
| SCHEMBL3412123 | 0.81 | TSHR (0.61) | TSHRALDH1A1THRBUSP2CYP3A4 | |
| SCHEMBL12621226 | 0.81 | KDM4E (0.53) | TSHRALDH1A1THRBADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2441783-A1 | Polymerizable composition and lithographic printing plate precursor including the same, and lithographic printing method | FUJIFILM Corporation (JP) | 2012-04-18 | — | — | EP | disclosed |