Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL17537078 | 0.92 | DPP4 (0.35) | SCN5ASCN9ASCN10ANLRP3ALOX15 | |
| SCHEMBL17549499 | 0.91 | SCN5A (0.34) | SCN5ASCN9ASCN10ANLRP3ALOX15 | |
| SCHEMBL17549493 | 0.85 | SCN5A (0.34) | SCN5ASCN9ASCN10AALOX15TSHR | |
| SCHEMBL23299314 | 0.85 | SCN5A (0.39) | SCN5ASCN9ASCN10ANLRP3 | |
| SCHEMBL23299320 | 0.85 | SCN5A (0.39) | SCN5ASCN9ASCN10ANLRP3 | |
| SCHEMBL17537132 | 0.85 | SCN5A (0.38) | SCN5ASCN9ASCN10AALOX15TSHR | |
| Trifluoroacetic Acid SCHEMBL28110534 | 0.84 | DPP4 (0.34) | SCN5ASCN9ASCN10AHTR1AHTR7 | |
| Trifluoroacetic Acid SCHEMBL17537104 | 0.84 | DPP4 (0.34) | SCN5ASCN9ASCN10AHTR1AHTR7 | |
| SCHEMBL17537141 | 0.84 | SCN5A (0.34) | SCN5ASCN9ASCN10AALOX15TSHR | |
| SCHEMBL17549495 | 0.83 | LARS1 (0.33) | SCN5ASCN9ASCN10AALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2995604-B1 | PHENOL DERIVATIVE AND PREPARATION METHOD AND USE IN MEDICINE THEREOF | SICHUAN HAISCO PHARMACEUTICAL CO LTD (CN) | 2019-07-10 | — | — | EP | disclosed |
| US-9517988-B2 | Phenol derivative and preparation method and use in medicine thereof | SICHUAN HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2016-12-13 | — | — | US | disclosed |
| US-9517988-B2 | Phenol derivative and preparation method and use in medicine thereof | SICHUAN HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2016-12-13 | — | — | US | disclosed |
| EP-2995604-A1 | PHENOL DERIVATIVE AND PREPARATION METHOD AND USE IN MEDICINE THEREOF | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2016-03-16 | — | — | EP | disclosed |
| EP-2995604-A1 | PHENOL DERIVATIVE AND PREPARATION METHOD AND USE IN MEDICINE THEREOF | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2016-03-16 | — | — | EP | disclosed |
| US-20160060197-A1 | PHENOL DERIVATIVE AND PREPARATION METHOD AND USE IN MEDICINE THEREOF | SICHUAN HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2016-03-03 | — | — | US | disclosed |
| US-20160060197-A1 | PHENOL DERIVATIVE AND PREPARATION METHOD AND USE IN MEDICINE THEREOF | SICHUAN HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2016-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160060197-A1 | PHENOL DERIVATIVE AND PREPARATION METHOD AND USE IN MEDICINE THEREOF | CYP2D6, CYP2B6, CYP2A6 | SCN5A 1254/4885SCN9A 2831/4885SCN10A 2985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.