Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.38 |
| ▸ | NPC1 | O15118 | 7/20 | 0.38 |
| ▸ | RAB9A | P51151 | 7/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17552162 | 0.96 | SMN1; SMN2 (0.40) | CYP17A1SMN1; SMN2NPC1RAB9ARECQL | |
| SCHEMBL17549591 | 0.89 | SAE1 (0.40) | CYP17A1SMN1; SMN2NPC1RAB9ARECQL | |
| SCHEMBL24663651 | 0.85 | SMN1; SMN2 (0.49) | CYP17A1SMN1; SMN2NPC1RAB9ARECQL | |
| SCHEMBL17547614 | 0.85 | SAE1 (0.43) | CYP17A1SMN1; SMN2NPC1RAB9ARECQL | |
| SCHEMBL17549590 | 0.84 | SMN1; SMN2 (0.41) | CYP17A1SMN1; SMN2NPC1RAB9ARECQL | |
| SCHEMBL17550343 | 0.82 | SAE1 (0.39) | CYP17A1SMN1; SMN2NPC1RAB9ARECQL | |
| SCHEMBL20932894 | 0.81 | NPC1 (0.43) | CYP17A1SMN1; SMN2NPC1RAB9ARECQL | |
| SCHEMBL18530994 | 0.79 | SMN1; SMN2 (0.47) | CYP17A1SMN1; SMN2NPC1RAB9ARECQL | |
| SCHEMBL25917538 | 0.79 | NPC1 (0.41) | CYP17A1SMN1; SMN2NPC1RAB9ARECQL | |
| SCHEMBL27101330 | 0.78 | SMN1; SMN2 (0.46) | CYP17A1SMN1; SMN2NPC1RAB9ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160058112-A1 | ARTICLE OF FOOTWEAR WITH SOIL-SHEDDING PERFORMANCE | NIKE, INC. | 2016-03-03 | — | — | US | disclosed |