SCHEMBL17550776

SCHEMBL17550776

COCCOC(=O)Nc1ccc(Cc2ccc(NC(=O)OCC(O)(O)COC(=O)Nc3ccc(Cc4ccc(NC(=O)OCCO)cc4)cc3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SAE1 Q9UBE0 1/20 0.41
UBA2 Q9UBT2 1/20 0.41
NPC1 O15118 7/20 0.40
RAB9A P51151 7/20 0.40
CASP1 P29466 1/20 0.40
CYP17A1 P05093 1/20 0.39
SMN1; SMN2 Q16637 9/20 0.39
RECQL P46063 1/20 0.39
TP53 P04637 3/20 0.39
LMNA P02545 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
ALDH1A1 P00352 2/20 0.39
MAPK1 P28482 2/20 0.39
HPGD P15428 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
TSHR P16473 1/20 0.37
MAPT P10636 2/20 0.37
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17550343 0.96 SAE1 (0.39) SAE1UBA2NPC1RAB9ACASP1
SCHEMBL9947412 0.95 SAE1 (0.44) SAE1UBA2NPC1RAB9ACASP1
SCHEMBL17549590 0.92 SMN1; SMN2 (0.41) SAE1UBA2NPC1RAB9ACASP1
SCHEMBL25917536 0.90 NPC1 (0.44) SAE1UBA2NPC1RAB9ACASP1
SCHEMBL17549591 0.89 SAE1 (0.40) SAE1UBA2NPC1RAB9ACASP1
SCHEMBL17547614 0.85 SAE1 (0.43) SAE1UBA2NPC1RAB9ACASP1
SCHEMBL25917537 0.83 SMN1; SMN2 (0.50) SAE1UBA2NPC1RAB9ACASP1
SCHEMBL24663651 0.83 SMN1; SMN2 (0.49) SAE1UBA2NPC1RAB9ACASP1
SCHEMBL25917538 0.82 NPC1 (0.41) SAE1UBA2NPC1RAB9ACASP1
SCHEMBL11119637 0.82 SAE1 (0.49) SAE1UBA2NPC1RAB9ACASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230276898-A1 ARTICLES INCLUDING COATED FIBERS AND METHODS OF MAKING COATED FIBERS AND ARTICLES NIKE, INC. 2023-09-07 US disclosed
US-20170252722-A1 ARTICLES WITH SOIL-SHEDDING PERFORMANCE NIKE, INC. (US) 2017-09-07 US disclosed
US-20160058116-A1 ARTICLE OF FOOTWEAR WITH SOIL-SHEDDING PERFORMANCE NIKE, INC. 2016-03-03 US disclosed