Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14912114 | 0.85 | BTK (0.42) | BTK | |
| SCHEMBL10255707 | 0.85 | BTK (0.43) | BTKTYK2 | |
| SCHEMBL10255692 | 0.82 | BTK (0.44) | BTK | |
| SCHEMBL14912502 | 0.82 | BTK (0.46) | BTK | |
| SCHEMBL14912218 | 0.81 | MAP3K14 (0.32) | BTK | |
| SCHEMBL14912864 | 0.81 | MAP4K1 (0.36) | BTK | |
| SCHEMBL14911884 | 0.81 | BTK (0.46) | BTK | |
| SCHEMBL17135471 | 0.81 | BTK (0.47) | BTK | |
| SCHEMBL14914692 | 0.79 | BTK (0.41) | BTK | |
| SCHEMBL14912256 | 0.79 | BTK (0.47) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566869-B1 | PYRIDONE AND AZA-PYRIDONE COMPOUNDS AND METHODS OF USE | GILEAD CONNECTICUT INC (US) | 2016-03-02 | — | — | EP | disclosed |