Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2520567 | 0.89 | GRM5 (0.63) | GRM5 | |
| SCHEMBL2518845 | 0.80 | GRM5 (1.00) | GRM5 | |
| SCHEMBL2571334 | 0.79 | GRM5 (0.96) | GRM5 | |
| SCHEMBL2516161 | 0.75 | GRM5 (1.00) | GRM5 | |
| SCHEMBL2520275 | 0.75 | GRM5 (1.00) | GRM5 | |
| SCHEMBL13519053 | 0.74 | GRM5 (0.67) | GRM5 | |
| SCHEMBL2524522 | 0.73 | GRM5 (1.00) | GRM5 | |
| SCHEMBL2521614 | 0.73 | GRM5 (1.00) | GRM5 | |
| SCHEMBL31338743 | 0.73 | GRM5 (1.00) | GRM5 | |
| SCHEMBL31338747 | 0.73 | GRM5 (1.00) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558457-B1 | ARYLETHYNYL DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2016-03-09 | — | — | EP | disclosed |