Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 19/20 | 0.60 |
| ▸ | PDE4A | P27815 | 2/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL508969 | 0.89 | PDE4D (0.66) | PDE4DPDE4A | |
| SCHEMBL17554699 | 0.88 | PDE4D (0.59) | PDE4DPDE4A | |
| SCHEMBL510024 | 0.83 | PDE4D (0.63) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL508989 | 0.83 | PDE4D (0.80) | PDE4DPDE4A | |
| SCHEMBL509960 | 0.82 | PDE4D (0.66) | PDE4DPDE4A | |
| SCHEMBL508560 | 0.80 | PDE4D (0.68) | PDE4D | |
| SCHEMBL17554700 | 0.80 | PDE4D (0.63) | PDE4DPDE4A | |
| SCHEMBL508949 | 0.80 | PDE4D (0.83) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL509671 | 0.79 | PDE4D (0.65) | PDE4D | |
| SCHEMBL509950 | 0.78 | PDE4D (0.68) | PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379548-B1 | TRIAZOLOPYRIDINES AS PHOSPHODIESTERASE INHIBITORS FOR TREATMENT OF DERMAL DISEASES | LEO PHARMA AS (DK) | 2016-03-09 | — | — | EP | disclosed |