Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 3/20 | 0.55 |
| ▸ | SRC | P12931 | 2/20 | 0.43 |
| ▸ | LYN | P07948 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | TTK | P33981 | 7/20 | 0.42 |
| ▸ | WNT1 | P04628 | 3/20 | 0.40 |
| ▸ | GSK3B | P49841 | 3/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.39 |
| ▸ | CDK2 | P24941 | 3/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12492274 | 0.88 | FYN (0.56) | FYNSRCLYNBTKTTK | |
| SCHEMBL16331975 | 0.85 | FYN (0.54) | FYNSRCTTKWNT1GSK3B | |
| SCHEMBL16333021 | 0.85 | FYN (0.46) | FYNSRCLYNBTKTTK | |
| SCHEMBL16331434 | 0.84 | FYN (0.53) | FYNTTKWNT1GSK3BDYRK1A | |
| SCHEMBL12492817 | 0.82 | FYN (0.57) | FYNTTKWNT1GSK3BDYRK1A | |
| SCHEMBL12492914 | 0.82 | FYN (0.61) | FYNSRCLYNBTKTTK | |
| SCHEMBL12492967 | 0.81 | FYN (0.60) | FYNSRCLYNTTKWNT1 | |
| SCHEMBL16332466 | 0.80 | FYN (0.54) | FYNSRCLYNBTKFGFR1 | |
| SCHEMBL12492438 | 0.80 | FYN (0.55) | FYNSRCLYNTTKWNT1 | |
| SCHEMBL12492484 | 0.80 | FYN (0.59) | FYNTTKWNT1GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2686318-B1 | PYRROLOPYRIDINEAMINO DERIVATIVES AS MPS1 INHIBITORS | CANCER REC TECH LTD (GB) | 2016-03-09 | — | — | EP | disclosed |