Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 17/20 | 0.55 |
| ▸ | EML4 | Q9HC35 | 6/20 | 0.48 |
| ▸ | SRPK1 | Q96SB4 | 9/20 | 0.48 |
| ▸ | SRPK2 | P78362 | 7/20 | 0.48 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27087579 | 0.86 | ALK (0.64) | ALKEML4SRPK1SRPK2 | |
| SCHEMBL7811871 | 0.86 | ALK (0.57) | ALKEML4SRPK1SRPK2DYRK3 | |
| SCHEMBL19988194 | 0.84 | SRPK1 (0.49) | ALKEML4SRPK1SRPK2DYRK3 | |
| SCHEMBL897390 | 0.83 | ALK (0.77) | ALKEML4SRPK1SRPK2DYRK3 | |
| SCHEMBL18252767 | 0.79 | ALK (0.52) | ALKEML4SRPK1SRPK2DYRK3 | |
| SCHEMBL29962607 | 0.79 | ALK (0.56) | ALK | |
| SCHEMBL897599 | 0.79 | ALK (0.56) | ALK | |
| SCHEMBL898181 | 0.79 | ALK (0.57) | ALK | |
| SCHEMBL29962794 | 0.79 | ALK (0.57) | ALK | |
| SCHEMBL898212 | 0.78 | ALK (0.48) | ALKEML4SRPK1SRPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2441753-A1 | TETRACYCLIC COMPOUND | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-04-18 | — | — | EP | disclosed |