Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.73 |
| ▸ | KIT | P10721 | 2/20 | 0.56 |
| ▸ | KDR | P35968 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1755745 | 0.92 | ALK (0.62) | ALKKITKDR | |
| SCHEMBL7806045 | 0.92 | ALK (0.65) | ALKKITKDR | |
| SCHEMBL7807321 | 0.92 | ALK (0.73) | ALKKITKDR | |
| SCHEMBL7807828 | 0.91 | ALK (0.75) | ALKKITKDR | |
| SCHEMBL1755795 | 0.91 | ALK (0.66) | ALKKITKDR | |
| SCHEMBL7810184 | 0.90 | ALK (0.75) | ALKKITKDR | |
| SCHEMBL7805398 | 0.90 | ALK (0.77) | ALKKITKDR | |
| SCHEMBL7805433 | 0.89 | ALK (0.75) | ALKKITKDR | |
| SCHEMBL7803004 | 0.89 | ALK (0.75) | ALKKITKDR | |
| SCHEMBL7812706 | 0.89 | ALK (0.63) | ALKKITKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2441753-A1 | TETRACYCLIC COMPOUND | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-04-18 | — | — | EP | disclosed |