Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.60 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7808869 | 0.93 | ALK (0.62) | ALKKDR | |
| SCHEMBL897373 | 0.87 | ALK (0.78) | ALKKDREML4 | |
| SCHEMBL7811636 | 0.86 | ALK (0.77) | ALKKDR | |
| SCHEMBL1755999 | 0.84 | ALK (0.58) | ALKKDREML4 | |
| SCHEMBL1755889 | 0.82 | ALK (0.49) | ALKEML4 | |
| SCHEMBL1755855 | 0.80 | ALK (0.62) | ALK | |
| SCHEMBL10283062 | 0.80 | ALK (0.78) | ALKKDR | |
| SCHEMBL1755850 | 0.80 | ALK (0.58) | ALKKDR | |
| SCHEMBL897530 | 0.80 | ALK (0.78) | ALKKDR | |
| SCHEMBL7814274 | 0.80 | ALK (0.77) | ALKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2441753-A1 | TETRACYCLIC COMPOUND | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010143664-A1 | TETRACYCLIC COMPOUND | 中外製薬株式会社 (JP) | 2010-12-16 | — | — | WO | disclosed |