Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7817678 | 0.93 | ALK (0.70) | ALK | |
| SCHEMBL20004321 | 0.91 | ALK (0.81) | ALK | |
| SCHEMBL21443325 | 0.90 | ALK (0.77) | ALK | |
| SCHEMBL1755958 | 0.90 | ALK (0.80) | ALK | |
| SCHEMBL898254 | 0.90 | ALK (0.80) | ALK | |
| SCHEMBL898368 | 0.90 | ALK (1.00) | ALK | |
| SCHEMBL1703737 | 0.90 | ALK (0.80) | ALK | |
| SCHEMBL898583 | 0.90 | ALK (0.86) | ALK | |
| SCHEMBL1703517 | 0.89 | ALK (0.85) | ALK | |
| SCHEMBL20356897 | 0.89 | ALK (0.85) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2441753-A1 | TETRACYCLIC COMPOUND | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010143664-A1 | TETRACYCLIC COMPOUND | 中外製薬株式会社 (JP) | 2010-12-16 | — | — | WO | disclosed |