Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21766989 | 0.89 | ALK (0.61) | ALK | |
| SCHEMBL20366431 | 0.89 | ALK (0.61) | ALK | |
| SCHEMBL897514 | 0.87 | ALK (1.00) | ALK | |
| SCHEMBL897513 | 0.87 | ALK (1.00) | ALK | |
| SCHEMBL10283686 | 0.87 | ALK (0.73) | ALK | |
| SCHEMBL897512 | 0.87 | ALK (1.00) | ALK | |
| SCHEMBL29962095 | 0.87 | ALK (1.00) | ALK | |
| SCHEMBL897126 | 0.86 | ALK (0.72) | ALK | |
| SCHEMBL20004128 | 0.83 | ALK (0.61) | ALK | |
| SCHEMBL7811110 | 0.76 | ALK (0.58) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |
| EP-2975024-A1 | TETRACYCLIC COMPOUNDS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2016-01-20 | — | — | EP | disclosed |
| EP-2441753-A1 | TETRACYCLIC COMPOUND | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-04-18 | — | — | EP | disclosed |