Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1756017 | 0.88 | ALK (0.75) | ALK | |
| SCHEMBL1703504 | 0.85 | ALK (0.75) | ALK | |
| SCHEMBL20366777 | 0.82 | ALK (0.66) | ALK | |
| SCHEMBL29962287 | 0.82 | ALK (0.83) | ALK | |
| SCHEMBL898523 | 0.82 | ALK (0.83) | ALK | |
| SCHEMBL16753050 | 0.82 | ALK (0.76) | ALK | |
| SCHEMBL898469 | 0.82 | ALK (0.76) | ALK | |
| SCHEMBL29962424 | 0.82 | ALK (0.76) | ALK | |
| SCHEMBL20004941 | 0.82 | ALK (0.88) | ALK | |
| SCHEMBL21443186 | 0.81 | ALK (0.75) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2441753-A1 | TETRACYCLIC COMPOUND | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-04-18 | — | — | EP | disclosed |