Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1755844 | 0.90 | ALK (0.55) | ALKMAPK14 | |
| SCHEMBL897050 | 0.90 | ALK (0.55) | ALK | |
| SCHEMBL10283402 | 0.90 | ALK (0.55) | ALK | |
| SCHEMBL897052 | 0.90 | ALK (0.55) | ALK | |
| SCHEMBL1756002 | 0.90 | ALK (0.53) | ALKMAPK14 | |
| SCHEMBL1755900 | 0.89 | ALK (0.54) | ALKMAPK14 | |
| SCHEMBL7813077 | 0.88 | ALK (0.55) | ALKMAPK14 | |
| SCHEMBL1755960 | 0.88 | ALK (0.55) | ALKMAPK14 | |
| SCHEMBL7812068 | 0.86 | ALK (0.54) | ALKMAPK14 | |
| SCHEMBL17636158 | 0.86 | ALK (0.55) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2441753-A1 | TETRACYCLIC COMPOUND | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010143664-A1 | TETRACYCLIC COMPOUND | 中外製薬株式会社 (JP) | 2010-12-16 | — | — | WO | disclosed |