SCHEMBL175601

SCHEMBL175601

CCCCCC(=O)NC(=O)CCCCC

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.65
FAAH O00519 4/20 0.62
ALDH1A1 P00352 3/20 0.59
MAPT P10636 2/20 0.59
KMT2A Q03164 3/20 0.58
MEN1 O00255 2/20 0.58
MAPK1 P28482 1/20 0.58
CES2 O00748 4/20 0.57
CES1 P23141 4/20 0.57
AKR1B1 P15121 1/20 0.55
KDM4E B2RXH2 1/20 0.53
PPARG P37231 6/20 0.52
PPARD Q03181 6/20 0.52
PPARA Q07869 6/20 0.52
HDAC11 Q96DB2 5/20 0.52
TSHR P16473 4/20 0.52
GPR84 Q9NQS5 4/20 0.52
TLR2 O60603 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
FABP4 P15090 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6684216 0.97 HSP90AA1 (0.70) HSP90AA1FAAHALDH1A1MAPTKMT2A
SCHEMBL1803511 0.97 HSP90AA1 (0.70) HSP90AA1FAAHALDH1A1MAPTKMT2A
SCHEMBL5932679 0.97 HSP90AA1 (0.70) HSP90AA1FAAHALDH1A1MAPTKMT2A
SCHEMBL31168145 0.97 HSP90AA1 (0.70) HSP90AA1FAAHALDH1A1MAPTKMT2A
SCHEMBL31520297 0.97 HSP90AA1 (0.70) HSP90AA1FAAHALDH1A1MAPTKMT2A
SCHEMBL10481745 0.97 HSP90AA1 (0.70) HSP90AA1FAAHALDH1A1MAPTKMT2A
SCHEMBL7769117 0.97 HSP90AA1 (0.70) HSP90AA1FAAHALDH1A1MAPTKMT2A
SCHEMBL19359738 0.97 HSP90AA1 (0.70) HSP90AA1FAAHALDH1A1MAPTKMT2A
SCHEMBL31607656 0.97 HSP90AA1 (0.70) HSP90AA1FAAHALDH1A1MAPTKMT2A
SCHEMBL28937158 0.97 HSP90AA1 (0.70) HSP90AA1FAAHALDH1A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3421454-B9 PIPERIDINE DERIVATIVE OTSUKA PHARMA CO LTD (JP) 2023-08-09 EP disclosed
EP-3421454-B1 PIPERIDINE DERIVATIVE OTSUKA PHARMA CO LTD (JP) 2023-04-05 EP disclosed
US-10851079-B2 Piperidine derivative OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2020-12-01 US disclosed
CN-211045362-U High-voltage power fuse AEM科技(苏州)股份有限公司 2020-07-17 CN disclosed
CN-110911254-A High-voltage power fuse and manufacturing method thereof AEM科技(苏州)股份有限公司 2020-03-24 CN disclosed
US-10464926-B2 Heterobicyclic compounds and their use for the treatment of tuberculosis OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2019-11-05 US disclosed
EP-3186240-B1 HETEROBICYCLIC COMPOUNDS AND THEIR USE FOR THE TREATMENT OF TUBERCULOSIS OTSUKA PHARMA CO LTD (JP) 2019-06-12 EP disclosed
US-20190040039-A1 PIPERIDINE DERIVATIVE OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2019-02-07 US disclosed
EP-3421454-A1 PIPERIDINE DERIVATIVE Otsuka Pharmaceutical Co., Ltd. (JP) 2019-01-02 EP disclosed
US-20180312488-A1 HETEROBICYCLIC COMPOUNDS AND THEIR USE FOR THE TREATMENT OF TUBERCULOSIS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2018-11-01 US disclosed
EP-1352650-A1 INHIBITORS AGAINST THE PRODUCTION AND RELEASE OF INFLAMMATORY CYTOKINES Institute of Medicinal Molecular Design, Inc. (JP) 2003-10-15 EP disclosed
US-6627288-B1 Optical recording medium and porphycene compound MITSUI CHEMICALS, INC. (JP) 2003-09-30 US disclosed
US-20030091931-A1 Benzbisazole compound and optical recording medium containing the compound MITSUI CHEMICALS, INC. (JP) 2003-05-15 US disclosed
EP-1262966-A2 Optical recording medium and novel azaporphyrin compound Mitsui Chemicals, Inc. (JP) 2002-12-04 EP disclosed
EP-1247655-A1 OPTICAL RECORDING MEDIUM AND NOVEL AZAPORPHYRIN COMPOUNDS Mitsui Chemicals, Inc. (JP) 2002-10-09 EP disclosed
EP-1245571-A1 BENZBISAZOLE COMPOUND AND OPTICAL RECORDING MEDIUM CONTAINING THE COMPOUND Mitsui Chemicals, Inc. (JP) 2002-10-02 EP disclosed
EP-1180765-A1 Optical recording medium and porphycene compound Mitsui Chemicals, Inc. (JP) 2002-02-20 EP disclosed
EP-0749974-B1 PHOSPHONIC DIESTER DERIVATIVE OTSUKA PHARMA CO LTD (JP) 2001-06-27 EP disclosed
US-5798344-A TREATING DIABETES, HYPERLIPIDEMIA OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 1998-08-25 US disclosed
EP-0749974-A1 PHOSPHONIC DIESTER DERIVATIVE OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 1996-12-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030091931-A1 Benzbisazole compound and optical recording medium containing the compound DAO, CACNA1I, KCNB2 HSP90AA1 4865/4885FAAH 1285/4885ALDH1A1 838/4885
US-10464926-B2 Heterobicyclic compounds and their use for the treatment of tuberculosis FNTB, SLC11A2, TBCD HSP90AA1 1915/4885FAAH 4729/4885ALDH1A1 1458/4885
US-20180312488-A1 HETEROBICYCLIC COMPOUNDS AND THEIR USE FOR THE TREATMENT OF TUBERCULOSIS FNTB, SLC11A2, TBCD HSP90AA1 1915/4885FAAH 4729/4885ALDH1A1 1458/4885
US-10851079-B2 Piperidine derivative EP300, SLC11A2, TBC1D5 HSP90AA1 1307/4885FAAH 3103/4885ALDH1A1 97/4885
US-20190040039-A1 PIPERIDINE DERIVATIVE EP300, SLC11A2, TBC1D5 HSP90AA1 1307/4885FAAH 3103/4885ALDH1A1 97/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.