Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | USP30 | Q70CQ3 | 8/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KDM5A | P29375 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | FPR3 | P25089 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17560314 | 1.00 | EPHX1 (0.55) | EPHX1HSD11B1CYP2C9USP30HDAC4 | |
| SCHEMBL2040388 | 1.00 | EPHX1 (0.55) | EPHX1HSD11B1CYP2C9USP30HDAC4 | |
| SCHEMBL10268244 | 0.91 | EPHX1 (0.65) | EPHX1ALDH1A1 | |
| SCHEMBL15175973 | 0.88 | NR1H2 (0.49) | EPHX1HSD11B1CYP2C9USP30ALDH1A1 | |
| SCHEMBL2000384 | 0.87 | EPHX1 (0.53) | EPHX1HSD11B1CYP2C9USP30HDAC4 | |
| SCHEMBL2000386 | 0.87 | EPHX1 (0.53) | EPHX1HSD11B1CYP2C9USP30HDAC4 | |
| SCHEMBL2000993 | 0.87 | EPHX1 (0.53) | EPHX1HSD11B1CYP2C9USP30HDAC4 | |
| SCHEMBL30505540 | 0.87 | EPHX1 (0.53) | EPHX1HSD11B1CYP2C9USP30HDAC4 | |
| SCHEMBL18632877 | 0.87 | EPHX1 (0.53) | EPHX1HSD11B1CYP2C9USP30HDAC4 | |
| SCHEMBL7456395 | 0.87 | EPHX1 (0.53) | EPHX1HSD11B1CYP2C9USP30HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112707893-B | 1-cyanopyrrolidine compounds as USP30 inhibitors | 特殊治疗有限公司 | 2023-10-31 | — | — | CN | disclosed |
| WO-2016034134-A1 | HETEROAROMATIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-03-10 | — | — | WO | disclosed |