SCHEMBL175628

SCHEMBL175628

C=CCOC(=O)CCc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 8/20 0.52
KMT2A Q03164 5/20 0.49
MEN1 O00255 4/20 0.44
ALDH1A1 P00352 5/20 0.43
TSHR P16473 4/20 0.43
NPSR1 Q6W5P4 3/20 0.43
CYP1A2 P05177 2/20 0.43
CYP3A4 P08684 2/20 0.43
MAPK1 P28482 2/20 0.43
BLM P54132 2/20 0.43
ATM Q13315 2/20 0.43
HIF1A Q16665 2/20 0.43
USP2 O75604 1/20 0.43
CYP2D6 P10635 1/20 0.43
MAPT P10636 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.41
XBP1 P17861 1/20 0.41
GPR55 Q9Y2T6 1/20 0.41
HTT P42858 2/20 0.40
PKM P14618 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17865625 0.93 TSHR (0.55) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL26328610 0.91 HSPA5 (0.46) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL8526807 0.89 GAA (0.55) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL1500632 0.86 GAA (0.55) GAAKMT2AMEN1ALDH1A1TSHR
Ethylene SCHEMBL4038426 0.85 GAA (0.57) GAAKMT2AMEN1ALDH1A1TSHR
Ethylene SCHEMBL1191582 0.85 GAA (0.57) GAAKMT2AMEN1ALDH1A1TSHR
Ethylene SCHEMBL1805199 0.85 GAA (0.57) GAAKMT2AMEN1ALDH1A1TSHR
Ethylene SCHEMBL6909288 0.85 GAA (0.57) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL9713873 0.85 APP (0.48) GAAALDH1A1TSHRNPSR1ATM
SCHEMBL858494 0.85 GAA (0.60) GAAKMT2AMEN1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 589 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109477014-B Refrigerator oil and composition for refrigerator 出光兴产株式会社 2022-11-01 CN claimed
EP-3263677-B1 BIODEGRADABLE LUBRICATING OIL COMPOSITION IDEMITSU KOSAN CO (JP) 2022-04-27 EP claimed
US-11060046-B2 Lubricating oil composition IDEMITSU KOSAN CO., LTD. (JP) 2021-07-13 US claimed
US-10377962-B2 Lubricant compositions containing controlled release additives EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2019-08-13 US claimed
US-10233298-B2 Polyurethane foams based on polyether carbonate polyols COVESTRO DEUTSCHLAND AG (DE) 2019-03-19 US claimed
EP-3420060-A1 LUBRICANT COMPOSITIONS CONTAINING CONTROLLED RELEASE ADDITIVES ExxonMobil Research and Engineering Company (US) 2019-01-02 EP claimed
US-20180282655-A1 LUBRICATING OIL COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2018-10-04 US claimed
US-20180044606-A1 BIODEGRADABLE LUBRICATING OIL COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2018-02-15 US claimed
EP-3272841-A1 LUBRICATING OIL COMPOSITION Idemitsu Kosan Co., Ltd (JP) 2018-01-24 EP claimed
EP-3263677-A1 BIODEGRADABLE LUBRICATING OIL COMPOSITION Idemitsu Kosan Co., Ltd (JP) 2018-01-03 EP claimed
EP-0151368-B1 PROCESS FOR THE PREPARATION OF A HYDROXYPHENYLCARBOXYLIC-ACID ESTER CIBA-GEIGY AG (CH) 1989-08-30 EP claimed
EP-0300056-A1 PROCESS FOR PREPARING TETRAKIS (3-(3,5-DI-tert-BUTYL-4-HYDROXYPHENYL)PROPIONYLOXYMETHYL)METHANE YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1989-01-25 EP claimed
EP-0300055-A1 PROCESS FOR PREPARING TETRAKIS(3-(3,5-DI-tert-BUTYL-4-HYDROXYPHENYL)PROPIONYLOXYMETHYL)METHANE Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1989-01-25 EP claimed
EP-0128368-B1 2,4,6-TRIS(SUBSTITUTED PHENOXY)-1,3,5,2,4,6-TRIOXATRIPHOSPHORINANES The B.F. GOODRICH Company (US) 1987-08-12 EP claimed
US-4618700-A ESTER INTERCHANGE OF PENTAERYTHRITOL WITH LOWER ALKYL-3-(3,5-DI-TERT-BUTYL-4-HYDROXYPHENYL)PROPIONATE CIBA-GEIGY CORPORATION (US) 1986-10-21 US claimed
EP-0027776-B1 PHENOLS AS STABILIZERS AND COMPOSITIONS CONTAINING THEM CIBA-GEIGY AG (CH) 1985-05-02 EP claimed
US-4507416-A 2,4,6-Tris(substituted phenoxy)-1,3,5,2,4,6-trioxatriphosphorinanes as stabilizers THE B. F. GOODRICH COMPANY (US) 1985-03-26 US claimed
EP-0128368-A1 2,4,6-Tris(substituted phenoxy)-1,3,5,2,4,6-trioxatriphosphorinanes The B.F. GOODRICH Company (US) 1984-12-19 EP claimed
US-4322303-A Dithiophosphate stabilizers CIBA-GEIGY CORPORATION (US) 1982-03-30 US claimed
EP-0027776-A1 Phenols as stabilizers and compositions containing them CIBA-GEIGY AG (CH) 1981-04-29 EP claimed