Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17563237 | 1.00 | KDM4E (0.39) | KDM4EALDH1A1MAPTSERPINE1LMNA | |
| SCHEMBL17563459 | 1.00 | KDM4E (0.39) | KDM4EALDH1A1MAPTSERPINE1LMNA | |
| SCHEMBL17563236 | 1.00 | KDM4E (0.39) | KDM4EALDH1A1MAPTSERPINE1LMNA | |
| SCHEMBL17563238 | 1.00 | KDM4E (0.39) | KDM4EALDH1A1MAPTSERPINE1LMNA | |
| SCHEMBL15503284 | 0.96 | KDM4E (0.41) | KDM4EALDH1A1MAPTSERPINE1LMNA | |
| SCHEMBL17563235 | 0.92 | CHRM2 (0.42) | KDM4EALDH1A1MAPTSERPINE1LMNA | |
| SCHEMBL15081559 | 0.92 | CHRM2 (0.42) | KDM4EALDH1A1MAPTSERPINE1LMNA | |
| SCHEMBL15503265 | 0.90 | CYP19A1 (0.42) | KDM4EALDH1A1MAPTSERPINE1LMNA | |
| SCHEMBL15503230 | 0.88 | KDM4E (0.33) | KDM4EALDH1A1MAPTSERPINE1LMNA | |
| SCHEMBL1080565 | 0.88 | SERPINE1 (0.38) | KDM4EALDH1A1MAPTSERPINE1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160068630-A1 | Process for Preparing Polycarbonates by Polymerization of Five-Membered-Ring Cyclic Carbonates | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2016-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160068630-A1 | Process for Preparing Polycarbonates by Polymerization of Five-Membered-Ring Cyclic Carbonates | CWC15, DKC1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | KDM4E 487/4885ALDH1A1 2195/4885MAPT 4641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.