SCHEMBL17565151

SCHEMBL17565151

CCCCCCOc1ccc(C)c(F)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR5A1 Q13285 1/20 0.53
TSHR P16473 2/20 0.51
THRA P10827 1/20 0.48
THRB P10828 1/20 0.48
TP53 P04637 2/20 0.47
LTA4H P09960 3/20 0.47
MRGPRX4 Q96LA9 1/20 0.47
PLA2G4B P0C869 1/20 0.46
HTR1A P08908 5/20 0.46
HTR1D P28221 5/20 0.46
HTR1B P28222 5/20 0.46
KDM4E B2RXH2 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
MAPT P10636 1/20 0.46
CYP2C9 P11712 1/20 0.46
HTR2A P28223 1/20 0.46
MAPK1 P28482 1/20 0.46
CYP2C19 P33261 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16705092 0.94 MRGPRX4 (0.47) NR5A1TSHRLTA4HMRGPRX4CYP1A2
SCHEMBL8454472 0.87 NR5A1 (0.55) NR5A1TSHRTP53LTA4HPLA2G4B
SCHEMBL17432926 0.87 MRGPRX4 (0.47) TSHRLTA4HMRGPRX4HTR1AHTR1B
SCHEMBL11036498 0.86 NR5A1 (0.53) NR5A1TSHRTHRATHRBTP53
SCHEMBL11369041 0.85 NR5A1 (0.56) NR5A1TSHRTHRATHRBTP53
SCHEMBL7784021 0.85 NR5A1 (0.52) NR5A1TSHRTP53LTA4HPLA2G4B
SCHEMBL14015787 0.85 NR5A1 (0.56) NR5A1TSHRTHRATHRBTP53
SCHEMBL11375096 0.85 NR5A1 (0.56) NR5A1TSHRTHRATHRBTP53
SCHEMBL9252588 0.85 NR5A1 (0.56) NR5A1TSHRTHRATHRBTP53
SCHEMBL16852407 0.85 PDK2 (0.43) NR5A1TSHRTHRATHRBTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4249461-A1 PHENOL COMPOUND, ELECTROCONDUCTIVE PASTE COMPOSITION, METHOD FOR PRODUCING ELECTROCONDUCTIVE PASTE COMPOSITION, AND ELECTROCONDUCTIVE WIRING LINE AND PRODUCTION METHOD THEREFOR SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-09-27 EP disclosed
US-9663466-B2 Aryl dihydropyridinones and piperidinone MGAT2 inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2017-05-30 US disclosed
EP-2687507-B1 NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND TAISHO PHARMACEUTICAL CO LTD (JP) 2016-03-09 EP disclosed