SCHEMBL17570201

SCHEMBL17570201

CC(=O)n1nc(-c2ccccc2)nc1-c1cccc(-c2nc(-c3ccccc3)nn2C(C)=O)c1

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 6/20 0.85
NR1H3 Q13133 6/20 0.85
F2 P00734 7/20 0.50
KMT2A Q03164 5/20 0.48
TSHR P16473 2/20 0.48
USP2 O75604 1/20 0.48
HSD17B10 Q99714 1/20 0.48
MAPT P10636 3/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2C9 P11712 1/20 0.48
HPGD P15428 1/20 0.48
CYP2C19 P33261 1/20 0.48
GAA P10253 1/20 0.48
RAB9A P51151 3/20 0.47
NPC1 O15118 1/20 0.47
POLB P06746 1/20 0.47
ALDH1A1 P00352 1/20 0.47
LMNA P02545 1/20 0.46
MAPK1 P28482 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17279678 0.94 NR1H2 (0.85) NR1H2NR1H3F2KMT2ATSHR
SCHEMBL10476799 0.92 NR1H2 (1.00) NR1H2NR1H3F2KMT2ATSHR
SCHEMBL17570200 0.90 NR1H2 (0.97) NR1H2NR1H3F2KMT2ATSHR
SCHEMBL10476808 0.86 NR1H2 (1.00) NR1H2NR1H3F2KMT2ATSHR
SCHEMBL18965806 0.86 NR1H2 (0.71) NR1H2NR1H3F2KMT2AHSD17B10
SCHEMBL11272510 0.82 NR1H2 (0.76) NR1H2NR1H3F2KMT2ATSHR
SCHEMBL17279824 0.80 NR1H2 (0.76) NR1H2NR1H3F2KMT2ATSHR
SCHEMBL17280013 0.78 NR1H2 (0.64) NR1H2NR1H3F2KMT2ATSHR
SCHEMBL11588462 0.78 NR1H2 (0.73) NR1H2NR1H3F2HSD17B10RAB9A
SCHEMBL11282178 0.77 NR1H2 (0.73) NR1H2NR1H3F2KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9720140-B2 Optical film, circularly polarizing plate and organic electroluminescent display device Konica Minolta, Inc. (JP) 2017-08-01 US disclosed
US-9720140-B2 Optical film, circularly polarizing plate and organic electroluminescent display device Konica Minolta, Inc. (JP) 2017-08-01 US disclosed
US-20160070030-A1 OPTICAL FILM, CIRCULARLY POLARIZING PLATE AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE Konica Minolta, Inc. (JP) 2016-03-10 US disclosed
US-20160070030-A1 OPTICAL FILM, CIRCULARLY POLARIZING PLATE AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE Konica Minolta, Inc. (JP) 2016-03-10 US disclosed