Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2931731 | 0.92 | IGF1R (0.85) | IGF1R | |
| SCHEMBL2936560 | 0.90 | IGF1R (1.00) | IGF1R | |
| SCHEMBL4027115 | 0.90 | IGF1R (0.87) | IGF1R | |
| SCHEMBL2942038 | 0.88 | IGF1R (0.86) | IGF1R | |
| SCHEMBL2940674 | 0.88 | IGF1R (0.84) | IGF1R | |
| SCHEMBL31573114 | 0.88 | IGF1R (0.84) | IGF1R | |
| SCHEMBL2934992 | 0.88 | IGF1R (0.84) | IGF1R | |
| SCHEMBL2939001 | 0.87 | IGF1R (1.00) | IGF1R | |
| SCHEMBL2932190 | 0.87 | IGF1R (0.82) | IGF1R | |
| SCHEMBL3732832 | 0.86 | IGF1R (0.81) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016036796-A1 | CYCLIC UREA COMPOUNDS AS TROPOMYOSIN-RELATED KINASE (TRK) INHIBITORS | GENZYME CORPORATION (US) | 2016-03-10 | — | — | WO | disclosed |