Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31643652 | 0.87 | MAPT (0.51) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL3221392 | 0.86 | MAPT (0.47) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL16242750 | 0.84 | GRM2 (0.48) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL29996307 | 0.84 | MAPT (0.44) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL18662462 | 0.84 | MAPT (0.44) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL3660644 | 0.83 | MAPT (0.66) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL23121012 | 0.83 | MAPT (0.53) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL29996551 | 0.83 | MAPT (0.53) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL16242633 | 0.82 | GRM2 (0.50) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL10687937 | 0.81 | SMN1; SMN2 (0.59) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170303574-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING SWEET TASTE | CHROMOCELL CORPORATION (US) | 2017-10-26 | — | — | US | disclosed |
| US-20170303574-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING SWEET TASTE | CHROMOCELL CORPORATION (US) | 2017-10-26 | — | — | US | disclosed |
| US-20170303574-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING SWEET TASTE | CHROMOCELL CORPORATION (US) | 2017-10-26 | — | — | US | disclosed |
| WO-2016036980-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING SWEET TASTE | CHROMOCELL CORPORATION (US) | 2016-03-10 | — | — | WO | disclosed |