Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 8/20 | 0.50 |
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.50 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.47 |
| ▸ | LPAR6 | P43657 | 2/20 | 0.47 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.47 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26305070 | 0.95 | LPAR3 (0.43) | LPAR1LPAR3LPAR2TSHRPLA2G2C | |
| SCHEMBL27606019 | 0.91 | LPAR1 (0.50) | LPAR1LPAR3LPAR2TSHRPLA2G2C | |
| SCHEMBL2234079 | 0.89 | CNR1 (0.55) | LPAR1LPAR3LPAR2TSHRPLA2G2C | |
| SCHEMBL2233827 | 0.89 | CNR1 (0.55) | LPAR1LPAR3LPAR2TSHRPLA2G2C | |
| SCHEMBL2232371 | 0.89 | CNR1 (0.55) | LPAR1LPAR3LPAR2TSHRPLA2G2C | |
| SCHEMBL707510 | 0.89 | CNR1 (0.55) | LPAR1LPAR3LPAR2TSHRPLA2G2C | |
| SCHEMBL2231650 | 0.89 | CNR1 (0.55) | LPAR1LPAR3LPAR2TSHRPLA2G2C | |
| SCHEMBL8746895 | 0.89 | TSHR (0.52) | LPAR1LPAR3LPAR2TSHRPLA2G2C | |
| SCHEMBL31238653 | 0.88 | LPAR3 (0.44) | LPAR1LPAR3LPAR2TSHRPLA2G2C | |
| SCHEMBL17641330 | 0.88 | TSHR (0.50) | LPAR1LPAR3LPAR2TSHRPLA2G2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2604614-B1 | Oxidized phospholipids | VASCULAR BIOGENICS LTD (IL) | 2016-03-09 | — | — | EP | disclosed |