Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.76 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131219 | 0.92 | AR (0.88) | ARHTTHIF1AKMT2AMAPT | |
| SCHEMBL12515785 | 0.92 | AR (0.88) | ARHTTHIF1AKMT2AMAPT | |
| SCHEMBL16281213 | 0.91 | AR (0.85) | ARHTTHIF1AKMT2AMAPT | |
| SCHEMBL2768639 | 0.89 | HIF1A (0.59) | ARHTTHIF1AKMT2AMAPT | |
| SCHEMBL15257224 | 0.87 | AR (1.00) | ARHTTHIF1AKMT2AMAPT | |
| SCHEMBL13736034 | 0.87 | AR (1.00) | ARHTTHIF1AKMT2AMAPT | |
| SCHEMBL13189123 | 0.87 | AR (0.78) | ARHTTHIF1AKMT2AMAPT | |
| SCHEMBL12989741 | 0.87 | AR (1.00) | ARHTTHIF1AKMT2AMAPT | |
| SCHEMBL16232997 | 0.87 | AR (0.78) | ARHTTHIF1AKMT2AMAPT | |
| SCHEMBL12267194 | 0.87 | AR (1.00) | ARHTTHIF1AKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2994451-A1 | ESTER DERIVATIVES OF ANDROGEN RECEPTOR MODULATORS AND METHODS FOR THEIR USE | British Columbia Cancer Agency Branch (CA) | 2016-03-16 | — | — | EP | disclosed |