Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17586340 | 0.92 | GSK3B (0.83) | GSK3B | |
| SCHEMBL12889246 | 0.91 | GSK3B (0.85) | GSK3B | |
| SCHEMBL17586344 | 0.85 | GSK3B (0.73) | GSK3B | |
| SCHEMBL1187995 | 0.85 | GSK3B (0.87) | GSK3B | |
| SCHEMBL8100177 | 0.85 | GSK3B (0.86) | GSK3B | |
| SCHEMBL17586390 | 0.84 | GSK3B (0.83) | GSK3B | |
| SCHEMBL17586346 | 0.84 | GSK3B (0.69) | GSK3B | |
| SCHEMBL1186150 | 0.83 | GSK3B (0.83) | GSK3B | |
| SCHEMBL8093215 | 0.83 | GSK3B (0.89) | GSK3B | |
| SCHEMBL1186210 | 0.83 | GSK3B (1.00) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203459-B1 | SPIROCYCLIC AMINOQUINOLONES AS GSK-3 INHIBITORS | KYORIN SEIYAKU KK (JP) | 2016-03-16 | — | — | EP | disclosed |