Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 14/20 | 0.62 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.37 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1757693 | 0.90 | PTGDR2 (0.62) | PTGDR2MEN1KMT2A | |
| SCHEMBL1757466 | 0.89 | PTGDR2 (0.78) | PTGDR2 | |
| SCHEMBL1759181 | 0.86 | PTGDR2 (0.63) | PTGDR2MAPTMEN1KMT2A | |
| SCHEMBL1757764 | 0.83 | PTGDR2 (0.82) | PTGDR2 | |
| SCHEMBL1757499 | 0.81 | PTGDR2 (0.77) | PTGDR2 | |
| SCHEMBL1757162 | 0.81 | PTGDR2 (0.67) | PTGDR2 | |
| SCHEMBL1757412 | 0.80 | PTGDR2 (0.59) | PTGDR2MEN1KMT2A | |
| SCHEMBL1757777 | 0.80 | PTGDR2 (0.66) | PTGDR2MAPTKMT2A | |
| SCHEMBL1757153 | 0.80 | PTGDR2 (0.82) | PTGDR2KMT2A | |
| SCHEMBL1757835 | 0.79 | PTGDR2 (0.62) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011055270-A1 | INDOLE BASED RECEPTOR CRTH2 ANTAGONISTS | WYETH LLC (US) | 2011-05-12 | — | — | WO | disclosed |