Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3268703 | 1.00 | ACE (0.42) | ACECYP3A4ALOX15MEN1KMT2A | |
| SCHEMBL21075662 | 0.85 | ACE (0.44) | ACECYP3A4ALOX15MEN1KMT2A | |
| SCHEMBL19083903 | 0.85 | ACE (0.44) | ACECYP3A4ALOX15MEN1KMT2A | |
| SCHEMBL3265345 | 0.85 | PREP (0.37) | PREP | |
| SCHEMBL4800813 | 0.81 | ACE (0.47) | ACEMEN1KMT2APREP | |
| SCHEMBL13609889 | 0.81 | ACE (0.47) | ACEMEN1KMT2APREP | |
| SCHEMBL29511169 | 0.81 | ACE (0.47) | ACEMEN1KMT2APREP | |
| SCHEMBL19075598 | 0.81 | ACE (0.41) | ACECYP3A4ALOX15MEN1KMT2A | |
| SCHEMBL9403912 | 0.80 | ACE (0.51) | ACECYP3A4ALOX15MEN1KMT2A | |
| SCHEMBL14408459 | 0.80 | ACE (0.43) | ACECYP3A4ALOX15MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3404030-A1 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2018-11-21 | — | — | EP | disclosed |
| EP-3386504-A2 | THERAPEUTIC INHIBITORY COMPOUNDS | Lifesci Pharmaceuticals, Inc. (BB) | 2018-10-17 | — | — | EP | disclosed |
| EP-3239152-A1 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2017-11-01 | — | — | EP | disclosed |
| WO-2017098328-A2 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHAMACEUTICALS, INC. (BB) | 2017-06-15 | — | — | WO | disclosed |
| EP-2635588-A1 | CONDENSED IMIDAZOLYLIMIDAZOLES AS ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2013-09-11 | — | — | EP | disclosed |
| WO-2013075029-A1 | CONDENSED IMIDAZOLYLIMIDAZOLES AS ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2013-05-23 | — | — | WO | disclosed |
| WO-2011059887-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-05-19 | — | — | WO | disclosed |