⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethane Dimethane Sulfonate SCHEMBL4140371 | 0.85 | USP2 (0.67) | — | |
| Ethane Dimethane Sulfonate SCHEMBL4143911 | 0.85 | USP2 (0.67) | — | |
| Ethane Dimethane Sulfonate SCHEMBL4154177 | 0.85 | USP2 (0.67) | — | |
| Ethane Dimethane Sulfonate SCHEMBL4148513 | 0.85 | USP2 (0.67) | — | |
| Ethane Dimethane Sulfonate SCHEMBL4149477 | 0.85 | USP2 (0.67) | — | |
| Ethane Dimethane Sulfonate SCHEMBL1336145 | 0.85 | USP2 (0.75) | — | |
| SCHEMBL4154180 | 0.77 | USP2 (0.63) | — | |
| SCHEMBL4140372 | 0.77 | USP2 (0.63) | — | |
| SCHEMBL267542 | 0.77 | USP2 (0.63) | — | |
| SCHEMBL16559900 | 0.77 | USP2 (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9017645-B2 | Homoglutamic acid derivatives | PIRAMAL IMAGING SA (CH) | 2015-04-28 | — | — | US | disclosed |
| US-20130071327-A1 | HOMOGLUTAMIC ACID DERIVATIVES | PIRAMAL IMAGING SA (CH) | 2013-03-21 | — | — | US | disclosed |
| EP-2499113-A1 | HOMOGLUTAMIC ACID DERIVATIVES | Bayer Pharma Aktiengesellschaft (DE) | 2012-09-19 | — | — | EP | disclosed |
| WO-2011057986-A1 | HOMOGLUTAMIC ACID DERIVATIVES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-05-19 | — | — | WO | disclosed |
| EP-2322500-A1 | Fluoro-labeled homo-glutamate derivatives and precursors thereof | Bayer Schering Pharma Aktiengesellschaft (DE) | 2011-05-18 | — | — | EP | disclosed |
| EP-2322514-A1 | Homoglutamic acid and glutamic acid derivatives | Bayer Schering Pharma Aktiengesellschaft (DE) | 2011-05-18 | — | — | EP | disclosed |