Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 11/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1759164 | 0.90 | PTGDR2 (0.61) | PTGDR2 | |
| SCHEMBL1757715 | 0.89 | PTGDR2 (0.66) | PTGDR2 | |
| SCHEMBL1759190 | 0.88 | PTGDR2 (0.68) | PTGDR2 | |
| SCHEMBL1757732 | 0.86 | PTGDR2 (0.58) | PTGDR2 | |
| SCHEMBL1757993 | 0.84 | PTGDR2 (0.46) | PTGDR2ALDH1A1MAPK1STAT3KDM4E | |
| SCHEMBL1758070 | 0.82 | PTGDR2 (0.43) | PTGDR2ALDH1A1MAPK1STAT3KDM4E | |
| SCHEMBL1757736 | 0.79 | PTGDR2 (0.59) | PTGDR2 | |
| SCHEMBL1757754 | 0.78 | PTGDR2 (0.72) | PTGDR2ALDH1A1MAPK1STAT3KDM4E | |
| SCHEMBL1759473 | 0.77 | PTGDR2 (0.60) | PTGDR2 | |
| SCHEMBL1757745 | 0.77 | PTGDR2 (0.69) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011055270-A1 | INDOLE BASED RECEPTOR CRTH2 ANTAGONISTS | WYETH LLC (US) | 2011-05-12 | — | — | WO | disclosed |