Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 0.64 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | PTGIR | P43119 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1758038 | 0.86 | PTGDR2 (0.49) | PTGDR2PTGDRCYP2C9 | |
| SCHEMBL1757636 | 0.81 | PTGDR2 (0.75) | PTGDR2PTGDRCYP2C9 | |
| SCHEMBL1757715 | 0.81 | PTGDR2 (0.66) | PTGDR2PTGDRCYP2C9PTGIR | |
| SCHEMBL1757654 | 0.80 | PTGDR2 (0.82) | PTGDR2PTGDRCYP2C9 | |
| SCHEMBL1757705 | 0.80 | PTGDR2 (0.73) | PTGDR2PTGDRCYP2C9 | |
| SCHEMBL1757965 | 0.79 | PTGDR2 (0.72) | PTGDR2PTGDRCYP2C9 | |
| SCHEMBL1757326 | 0.78 | PTGDR2 (0.79) | PTGDR2PTGDRCYP2C9 | |
| SCHEMBL1757692 | 0.78 | PTGDR2 (1.00) | PTGDR2PTGDRCYP2C9 | |
| SCHEMBL318291 | 0.78 | PTGDR2 (0.60) | PTGDR2PTGDRCYP2C9PTGIR | |
| SCHEMBL1757612 | 0.77 | PTGDR2 (0.78) | PTGDR2PTGDRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011055270-A1 | INDOLE BASED RECEPTOR CRTH2 ANTAGONISTS | WYETH LLC (US) | 2011-05-12 | — | — | WO | disclosed |