Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 13/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14741135 | 1.00 | KCNH2 (0.51) | KCNH2MCHR1WDR5NOTUMTLR9 | |
| SCHEMBL14745538 | 0.92 | KCNH2 (0.42) | KCNH2MCHR1WDR5NOTUM | |
| SCHEMBL14741004 | 0.88 | KCNH2 (0.38) | KCNH2NOTUM | |
| SCHEMBL14745225 | 0.88 | PRKD3 (0.44) | KCNH2NOTUM | |
| Trifluoroacetic Acid SCHEMBL17595148 | 0.87 | KCNH2 (0.53) | KCNH2MCHR1WDR5 | |
| Trifluoroacetic Acid SCHEMBL14741133 | 0.87 | KCNH2 (0.53) | KCNH2MCHR1WDR5 | |
| SCHEMBL14744736 | 0.86 | TOP1 (0.39) | KCNH2 | |
| SCHEMBL14758835 | 0.85 | KCNH2 (0.57) | KCNH2MCHR1WDR5 | |
| SCHEMBL14745687 | 0.85 | KCNH2 (0.57) | KCNH2MCHR1WDR5 | |
| SCHEMBL14758820 | 0.85 | KCNH2 (0.57) | KCNH2MCHR1WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016039936-A2 | MONOCYCLIC SUBSTITUTED 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-03-17 | — | — | WO | claimed |