⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14964975 | 0.90 | — | — | |
| SCHEMBL14965093 | 0.90 | — | — | |
| SCHEMBL17599010 | 0.90 | — | — | |
| SCHEMBL16293145 | 0.85 | — | — | |
| SCHEMBL14965263 | 0.84 | — | — | |
| SCHEMBL14965484 | 0.81 | — | — | |
| SCHEMBL14965332 | 0.80 | — | — | |
| SCHEMBL16293367 | 0.80 | — | — | |
| SCHEMBL16293279 | 0.80 | — | — | |
| SCHEMBL16293880 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160152634-A1 | THIENO- AND FURO - PYRIMIDINES AND PYRIDINES, USEFUL AS POTASSIUM CHANNEL INHIBITORS | XENTION LTD (GB) | 2016-06-02 | — | — | US | disclosed |
| US-9290511-B2 | Thieno-pyrimidines, useful as potassium channel inhibitors | XENTION LIMITED (GB) | 2016-03-22 | — | — | US | disclosed |