SCHEMBL1759953

SCHEMBL1759953

Cc1cc(C=O)on1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8868760 0.78
SCHEMBL4086630 0.76
SCHEMBL8384934 0.76
SCHEMBL5704548 0.74
SCHEMBL5704550 0.74
SCHEMBL5704559 0.74
SCHEMBL10646652 0.73 HCAR2 (0.41)
SCHEMBL18237505 0.73 HDAC1 (0.54)
SCHEMBL8815797 0.71
SCHEMBL9823480 0.71 HDAC1 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 283 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102812011-A [1,5] -diazacyclo-octatetraene derivative MELLITECH 2012-12-05 CN claimed
EP-2501685-A1 [1,5]-DIAZOCIN DERIVATIVES Mellitech (FR) 2012-09-26 EP claimed
US-20120225892-A1 [1,5]-Diazocin Derivatives MELLITECH (FR) 2012-09-06 US claimed
WO-2011058193-A1 [1,5]-DIAZOCIN DERIVATIVES MELLITECH (FR) 2011-05-19 WO claimed
EP-0207684-B1 7-Oxabicycloheptane substituted diamide and its congener prostaglandin analogs SQUIBB & SONS INC (US) 1994-11-23 EP claimed
US-5270313-A Treatment of circulatory disorders HOFFMANN-LA ROCHE INC. (US) 1993-12-14 US claimed
EP-0258914-A2 Rhodanine derivatives and a process for preparing same TAIHO PHARMACEUTICAL CO., LTD. (JP) 1988-03-09 EP claimed
US-4439433-A CEPHALOSPORIN ANTIBIOTICS ROUSSEL UCLAF (FR) 1984-03-27 US claimed
US-4307090-A CEPHALOSPORINS - BACTERICIDES ROUSSEL UCLAF (FR) 1981-12-22 US claimed
JP-62238286-A None JP disclosed
JP-61027984-A None JP disclosed
US-20260078091-A1 Piperidinone Derivatives as MDM2 Inhibitors for the Treatment of Cancer AMGEN INC (US) 2026-03-19 US disclosed
WO-2025111492-A1 INHIBITORS OF PARG 858 THERAPEUTICS, INC. (US) 2025-05-30 WO disclosed
CN-113710668-B Condensed azines for EP300 or CBP modulation and indications thereof OPNA生物公司 2025-01-07 CN disclosed
EP-0041675-A2 4-Halogen-5-(trichloromethyl-phenyl)-oxazole derivatives, process for preparing them and radiation-sensitive compositions containing them HOECHST AKTIENGESELLSCHAFT (DE) 1981-12-16 EP disclosed
US-4243812-A REACTING A 5-ACETYLISOXAZOLE WITH A LOWER ALKYL NITRITE TAIHO PHARMACEUTICAL COMPANY (JP) 1981-01-06 US disclosed
US-4224450-A REACTING CORRESPONDING ALDEHYDE WITH NITROMETHANE TAIHO PHARMACEUTICAL COMPANY (JP) 1980-09-23 US disclosed
US-4212874-A Glyoxal-2-oxim derivatives and a process for relieving pain/or inflammation therewith TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) 1980-07-15 US disclosed
US-4017313-A Photosensitive composition containing a leuco dye, a photosensitizer, an aromatic aldehyde and a secondary or tertiary amine and the use thereof in a direct-print process E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-04-12 US disclosed
JP-S06127984-A 0001-01-01 JP disclosed