Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3608264 | 0.80 | TAAR1 (0.74) | TAAR1 | |
| SCHEMBL3608269 | 0.80 | TAAR1 (0.74) | TAAR1 | |
| SCHEMBL3614077 | 0.80 | TAAR1 (0.74) | TAAR1 | |
| SCHEMBL1759897 | 0.80 | TAAR1 (0.56) | TAAR1 | |
| SCHEMBL1760040 | 0.80 | TAAR1 (0.56) | TAAR1 | |
| SCHEMBL17135593 | 0.79 | TAAR1 (0.55) | TAAR1 | |
| SCHEMBL1760041 | 0.71 | TAAR1 (0.56) | TAAR1 | |
| SCHEMBL1760308 | 0.71 | TAAR1 (0.56) | TAAR1 | |
| SCHEMBL12234413 | 0.71 | TAAR1 (0.50) | TAAR1 | |
| SCHEMBL1760049 | 0.70 | TAAR1 (0.79) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3463359-A1 | TRACE AMINE ASSOCIATED RECEPTOR 1 AGONISTS AND PARTIAL AGONISTS FOR PAIN TREATMENT | Purdue Pharma LP (US) | 2019-04-10 | — | — | EP | disclosed |
| WO-2017210616-A1 | TRACE AMINE ASSOCIATED RECEPTOR 1 AGONISTS AND PARTIAL AGONISTS FOR PAIN TREATMENT | PURDUE PHARMA L.P. (US) | 2017-12-07 | — | — | WO | disclosed |
| EP-2499121-A1 | OXAZOLINE DERIVATIVES FOR TREATMENT OF CNS DISORDERS. | F. Hoffmann-La Roche AG (CH) | 2012-09-19 | — | — | EP | disclosed |
| WO-2011057973-A1 | OXAZOLINE DERIVATIVES FOR TREATMENT OF CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-05-19 | — | — | WO | disclosed |