⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL621215 | 0.92 | — | — | |
| SCHEMBL25374210 | 0.90 | TSHR (0.42) | — | |
| SCHEMBL8211305 | 0.90 | TSHR (0.42) | — | |
| SCHEMBL8371875 | 0.90 | TSHR (0.42) | — | |
| SCHEMBL15809383 | 0.90 | TSHR (0.42) | — | |
| SCHEMBL5856218 | 0.90 | TSHR (0.42) | — | |
| SCHEMBL3932453 | 0.83 | — | — | |
| SCHEMBL2122507 | 0.76 | — | — | |
| SCHEMBL10604585 | 0.75 | — | — | |
| SCHEMBL10604584 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009005839-A2 | COMPOUNDS AND METHODS OF USE | THE GOVERNMENT OF THE U.S.A. AS REPRESENTED BY THE SECRETARY OF THE DEPT. OF HEALTH & HUMAN SERVICE (US) | 2009-01-08 | — | — | WO | claimed |
| US-12540073-B2 | Heterogeneous hydrogen-catalyst solid fuel reaction mixture and reactor | BRILLIANT LIGHT POWER, INC. (US) | 2026-02-03 | — | — | US | disclosed |
| US-20230045778-A9 | HETEROGENEOUS HYDROGEN-CATALYST SOLID FUEL REACTION MIXTURE AND REACTOR | BRILLIANT LIGHT POWER, INC. (US) | 2023-02-09 | — | — | US | disclosed |
| US-20200299130-A1 | HETEROGENEOUS HYDROGEN-CATALYST REACTOR | BRILLIANT LIGHT POWER, INC. (US) | 2020-09-24 | — | — | US | disclosed |
| CN-110446764-A | Method for producing Silicone-based adhesives | DOW CORNING TORAY CO LTD | 2019-11-12 | — | — | CN | disclosed |
| US-9980928-B2 | Hydroxy aliphatic substituted phenyl aminoalkyl ether derivatives | PROUS INSTITUTE FOR BIOMEDICAL RESEARCH, S.A. (ES) | 2018-05-29 | — | — | US | disclosed |
| US-20170239197-A1 | HYDROXY ALIPHATIC SUBSTITUTED PHENYL AMINOALKYL ETHER DERIVATIVES | PROUS INSTITUTE FOR BIOMEDICAL RESEARCH, S.A. (ES) | 2017-08-24 | — | — | US | disclosed |
| US-9624158-B2 | Hydroxy aliphatic substituted phenyl aminoalkyl ether derivatives | PROUS INSTITUTE FOR BIOMEDICAL RESEARCH, S.A. (ES) | 2017-04-18 | — | — | US | disclosed |
| EP-2945702-B1 | HYDROXY ALIPHATIC SUBSTITUTED PHENYL AMINOALKYL ETHER DERIVATIVES | PROUS INST FOR BIOMEDICAL RES S A (ES) | 2017-01-11 | — | — | EP | disclosed |
| US-20150344408-A1 | HYDROXY ALIPHATIC SUBSTITUTED PHENYL AMINOALKYL ETHER DERIVATIVES | PROUS INSTITUTE FOR BIOMEDICAL RESEARCH, S.A. (ES) | 2015-12-03 | — | — | US | disclosed |
| EP-0570245-B1 | Octahydronaphthalene oxime derivatives for cholesterol biosynthesis inhibition, their preparation and use | SANKYO CO (JP) | 1996-10-30 | — | — | EP | disclosed |
| US-5534654-A | ANTITUMOR, ANTIINFLAMMATORY, INHIBITOR OF LYMPHOCYTE ADHESIVE FACTORS | SHIONOGI & CO., LTD. (JP) | 1996-07-09 | — | — | US | disclosed |
| US-5403860-A | Octahydronaphthalene oxime compounds for cholesterol synthesis inhibition | SANKYO COMPANY, LIMITED (JP) | 1995-04-04 | — | — | US | disclosed |
| EP-0570594-A1 | HYDROXAMIC ACID DERIVATIVE BASED ON AROMATIC SULFONAMIDE | SHIONOGI & CO., LTD. (JP) | 1993-11-24 | — | — | EP | disclosed |
| EP-0570245-A2 | Octahydronaphthalene oxime derivatives for cholesterol biosynthesis inhibition, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1993-11-18 | — | — | EP | disclosed |
| EP-0314435-B1 | OCTAHYDRONAPHTHALENE OXIME DERIVATIVES FOR CHOLESTEROL SYNTHESIS INHIBITION, PROCESSES FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | Sankyo Company Limited (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4997848-A | Enzyme inhibitors | SANKYO COMPANY, LIMITED (JP) | 1991-03-05 | — | — | US | disclosed |
| EP-0314435-A2 | Octahydronaphthalene oxime derivatives for cholesterol synthesis inhibition, processes for their preparation and compositions containing them | Sankyo Company Limited (JP) | 1989-05-03 | — | — | EP | disclosed |
| US-4144154-A | Polythiol accelerated radiation crosslinking of olefinically unsaturated polymers | ZAPP ROBERT L | 1979-03-13 | — | — | US | disclosed |
| US-4094757-A | Polythiol accelerated radiation crosslinking of olefinically unsaturated allylically halogenated polymers | ZAPP ROBERT L | 1978-06-13 | — | — | US | disclosed |