Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23747921 | 0.88 | ACACB (0.58) | ACACB | |
| SCHEMBL17583853 | 0.88 | ACACB (0.58) | ACACB | |
| SCHEMBL17583903 | 0.85 | ACACB (0.78) | ACACB | |
| SCHEMBL23747917 | 0.85 | ACACB (0.78) | ACACB | |
| SCHEMBL23774225 | 0.82 | ACACB (0.53) | ACACB | |
| SCHEMBL17585124 | 0.81 | ACACB (0.68) | ACACB | |
| SCHEMBL23747904 | 0.81 | ACACB (0.52) | ACACB | |
| SCHEMBL9605898 | 0.80 | PTPN1 (0.49) | ACACB | |
| SCHEMBL17583932 | 0.80 | ACACB (0.69) | ACACB | |
| SCHEMBL23747930 | 0.80 | ACACB (0.69) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3194367-A1 | TETRAHYDROISOQUINOLINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR THE TREATMENT OF OBESITY AND DIABETES | Boehringer Ingelheim International GmbH (DE) | 2017-07-26 | — | — | EP | disclosed |
| WO-2016041845-A1 | TETRAHYDROISOQUINOLINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR THE TREATMENT OF OBESITY AND DIABETES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-03-24 | — | — | WO | disclosed |