Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3722652 | 0.93 | FLT3 (0.48) | FYNFLT3KDM4ECYP1A2CYP3A4 | |
| SCHEMBL3720480 | 0.89 | TTK (0.43) | KMT2AMEN1TTK | |
| SCHEMBL120525 | 0.88 | TTK (0.42) | FLT3KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL120398 | 0.77 | TTK (0.52) | KMT2ASMN1; SMN2MEN1HIF1ATTK | |
| SCHEMBL121930 | 0.76 | KMT2A (0.47) | HPGDKMT2ASMN1; SMN2MAPK1MEN1 | |
| SCHEMBL3728821 | 0.76 | TTK (0.42) | KMT2ATTK | |
| SCHEMBL3811367 | 0.76 | TTK (0.48) | KMT2ATTK | |
| SCHEMBL121918 | 0.75 | FYN (0.51) | FYNFLT3KDM4EALDH1A1GAA | |
| SCHEMBL120513 | 0.75 | KMT2A (0.46) | KMT2AMEN1TTK | |
| SCHEMBL3723252 | 0.75 | TTK (0.44) | FYNTP53KMT2ATTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424537-A1 | SUBSTITUTED IMIDAZOQUINOXALINES | Bayer Pharma Aktiengesellschaft (DE) | 2012-03-07 | — | — | EP | claimed |